Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.65 |
| ▸ | SELP | P16109 | 1/20 | 0.65 |
| ▸ | SELE | P16581 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64932 | 0.86 | ALDH1A1 (0.58) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL13855810 | 0.80 | SELL (0.46) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL67584 | 0.80 | SELL (1.00) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL4396495 | 0.79 | ALDH1A1 (0.52) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL8990158 | 0.79 | HSD17B10 (0.43) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL17864586 | 0.79 | ACHE (0.65) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL7724614 | 0.79 | HPGD (0.56) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL23409889 | 0.75 | SELL (0.46) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL31200564 | 0.75 | SELL (0.46) | SELLSELPSELEALDH1A1RECQL | |
| SCHEMBL4544561 | 0.75 | ALDH1A1 (0.60) | SELLSELPSELEALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132603-A2 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2017-10-05 | — | — | US | disclosed |
| US-9334289-B2 | Cephem compound having catechol or pseudo-catechol structure | SHIONOGI & CO., LTD. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LTD (GB) | 2015-10-22 | — | — | US | disclosed |
| US-20140088302-A1 | NOVEL CEPHEM COMPOUND HAVING CATECHOL OR PSEUDO-CATECHOL STRUCTURE | SHIONOGI & CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| EP-2703406-A1 | NOVEL CEPHEM COMPOUND HAVING CATECHOL OR PSEUDO-CATECHOL STRUCTURE | Shionogi & Co., Ltd. (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-6759435-B1 | SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS | A.P. Group Inc. | 2004-07-06 | — | — | US | disclosed |
| EP-0257828-B1 | DIPROPARGYLOXYBENZENE COMPOUNDS AND THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4870064-A | PHYTOPATHOGEN FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0257828-A1 | Dipropargyloxybenzene compounds and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-02 | — | — | EP | disclosed |
| US-4011181-A | POLYURETHANE FOAMS CONTAINING STANNOUS CATECHOL DERIVATIVES | OLIN CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088302-A1 | NOVEL CEPHEM COMPOUND HAVING CATECHOL OR PSEUDO-CATECHOL STRUCTURE | COMT, CMBL, CEP170 | SELL 2569/4885SELP 2562/4885SELE 2265/4885 |
| US-20170281532-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | CEP170, CES2, CMBL | SELL 3556/4885SELP 3882/4885SELE 3639/4885 |
| US-20150299223-A1 | 2-SUBSTITUTED CEPHEM COMPOUNDS | CEP170, ABL1, CEPT1 | SELL 3068/4885SELP 2254/4885SELE 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.