SCHEMBL8990158

SCHEMBL8990158

Cc1cc(Cl)c(O)c(-c2cc(C)cc(Cl)c2O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.43
ALDH1A1 P00352 4/20 0.43
TSHR P16473 3/20 0.43
RECQL P46063 2/20 0.43
TTR P02766 1/20 0.43
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
SELE P16581 1/20 0.43
CYP3A4 P08684 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43
PLG P00747 1/20 0.43
PLAU P00749 1/20 0.43
PRSS1 P07477 1/20 0.43
HPGD P15428 2/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40
ACLY P53396 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64932 0.86 ALDH1A1 (0.58) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL4396495 0.79 ALDH1A1 (0.52) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL6841589 0.79 SELL (0.65) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL4544561 0.75 ALDH1A1 (0.60) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL10922054 0.75 TSHR (0.46) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL13855810 0.75 SELL (0.46) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL11624152 0.73 NPC1 (0.40) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL11624149 0.73 NPC1 (0.40) HSD17B10ALDH1A1TSHRRECQLTTR
SCHEMBL69852 0.73 HSPA5 (0.53) HSD17B10ALDH1A1TSHRRECQLTTR
Dimethylamine SCHEMBL11150585 0.73 ALDH1A1 (0.46) HSD17B10ALDH1A1TSHRRECQLTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP claimed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed