Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503239 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1TDP1TP53SMN1; SMN2 | |
| SCHEMBL6494111 | 0.83 | GFER (0.49) | KDM4EALDH1A1TDP1TP53SMN1; SMN2 | |
| SCHEMBL6503020 | 0.82 | GPBAR1 (0.58) | KDM4EALDH1A1GPBAR1TDP1TP53 | |
| Hydrochloric Acid SCHEMBL6501843 | 0.81 | GPBAR1 (0.57) | KDM4EALDH1A1GPBAR1TDP1TP53 | |
| SCHEMBL6493236 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1TDP1TP53SMN1; SMN2 | |
| SCHEMBL6495212 | 0.70 | ALDH1A1 (0.56) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL6262923 | 0.69 | ALDH1A1 (0.57) | KDM4EALDH1A1GPBAR1TDP1CCKAR | |
| SCHEMBL1381055 | 0.69 | LMNA (0.52) | KDM4EALDH1A1TP53SMN1; SMN2CCKAR | |
| SCHEMBL1381909 | 0.68 | GFER (0.54) | KDM4ETDP1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6415511 | 0.68 | ALDH1A1 (0.53) | KDM4EALDH1A1TP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | KDM4E 1246/4885ALDH1A1 240/4885GPBAR1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.