Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493373 | 0.82 | F2 (0.41) | BACE1F2TMPRSS6 | |
| SCHEMBL6495677 | 0.81 | KCNT1 (0.39) | — | |
| SCHEMBL6493493 | 0.80 | CTSS (0.40) | CTSDF2TMPRSS6 | |
| SCHEMBL6491914 | 0.79 | F2 (0.45) | F2TMPRSS6 | |
| SCHEMBL6481635 | 0.79 | F2 (0.40) | BACE1F2TMPRSS6 | |
| SCHEMBL6483914 | 0.78 | F2 (0.48) | F2TMPRSS6 | |
| SCHEMBL8790297 | 0.77 | GHSR (0.47) | — | |
| SCHEMBL6482720 | 0.77 | GHSR (0.47) | — | |
| SCHEMBL6481453 | 0.76 | CTSS (0.38) | BACE1F2TMPRSS6 | |
| SCHEMBL9421651 | 0.76 | CTSS (0.42) | F2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261332-A1 | Sulfonamides and uses thereof | ELIXIR PHARMACEUTICALS, INC. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261332-A1 | Sulfonamides and uses thereof | GLS2, STS, ABAT | BACE1 789/4885TNKS 3808/4885TNKS2 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.