Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481635 | 0.89 | F2 (0.40) | F2TMPRSS6CTSSCA12CA1 | |
| SCHEMBL6490939 | 0.88 | ALDH1A1 (0.32) | F2TMPRSS6CTSSALDH1A1GHSR | |
| SCHEMBL6483914 | 0.86 | F2 (0.48) | F2TMPRSS6ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6491914 | 0.86 | F2 (0.45) | F2TMPRSS6CTSSCA12CA1 | |
| SCHEMBL6493493 | 0.86 | CTSS (0.40) | F2TMPRSS6CTSSCA12CA1 | |
| SCHEMBL6481520 | 0.83 | F2 (0.36) | F2TMPRSS6CTSSSCN9AMMP1 | |
| SCHEMBL6481449 | 0.82 | F2 (0.39) | F2TMPRSS6CTSSSCN9AGHSR | |
| SCHEMBL6493363 | 0.82 | BACE1 (0.36) | F2TMPRSS6BACE1 | |
| SCHEMBL8790297 | 0.82 | GHSR (0.47) | CTSSGHSR | |
| SCHEMBL6482720 | 0.82 | GHSR (0.47) | CTSSGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261332-A1 | Sulfonamides and uses thereof | ELIXIR PHARMACEUTICALS, INC. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261332-A1 | Sulfonamides and uses thereof | GLS2, STS, ABAT | F2 4100/4885TMPRSS6 1396/4885CTSS 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.