Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17685570 | 0.85 | CES2 (0.48) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL27493394 | 0.83 | CES2 (0.47) | CES2CES1KEAP1ALOX5GSK3B | |
| Benzene SCHEMBL11551889 | 0.83 | CES2 (0.47) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL4574168 | 0.82 | ALOX5 (0.46) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL8853390 | 0.82 | ALOX5 (0.50) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL7723137 | 0.81 | CES2 (0.48) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL10969161 | 0.81 | CES2 (0.48) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL10821329 | 0.78 | ALOX5 (0.46) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL28131623 | 0.78 | CES2 (0.46) | CES2CES1KEAP1ALOX5GSK3B | |
| SCHEMBL5845615 | 0.78 | ALOX5 (0.50) | CES2CES1KEAP1ALOX5GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101052459-B | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same | TORAY INDUSTRIES | 2012-04-04 | — | — | CN | claimed |
| CN-101052459-A | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same | TORAY INDUSTRIES (JP) | 2007-10-10 | — | — | CN | claimed |
| CN-110194765-A | For controlling the composition and method of nematode | 孟山都技术有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-105418598-B | For controlling the composition and method of nematode | 孟山都技术有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-104892672-B | Chiral spiro phosphine-nitrogen-sulphur tridentate ligand and its preparation method and application | 浙江九洲药业股份有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-107266334-A | Fluorenes based compound, the Photoepolymerizationinitiater initiater containing the fluorenes based compound and the photo-sensitive composition containing the Photoepolymerizationinitiater initiater | 大东凯米克斯株式会社 | 2017-10-20 | — | — | CN | disclosed |
| CN-107007596-A | Method for treating posttraumatic stress disorder | 阿泽凡药物公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-103269584-B | Methods for treating post-traumatic stress disorder | 阿泽凡药物公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104140421-B | Benzo isothiazole compound and the application in antipsychotic drug is prepared | 上海医药工业研究院 | 2017-04-05 | — | — | CN | disclosed |
| CN-106459021-A | Compositions and methods for treating neurodegenerative diseases | 阿泽范药品公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104922117-A | BETA-LACTAMYLALKANOIC ACIDS FOR TREATING PREMENSTRUAL DISORDERS | AZEVAN PHARMACEUTICALS INC | 2015-09-23 | — | — | CN | disclosed |
| CN-1039908-C | Tricyclic diaza * vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1998-09-23 | — | — | CN | disclosed |
| CN-1184425-A | 5-substituted-3- (1,2,3, 6-tetrahydropyridin-4-yl) -and 3- (piperidin-4-yl) -1H-indoles, 5-HT1FAgonists | LILLY CO ELI (US) | 1998-06-10 | — | — | CN | disclosed |
| CN-1023482-C | Thiophen compouns and their preparation | SANDOZ LTD (CH) | 1994-01-12 | — | — | CN | disclosed |
| US-5032588-A | Non-steroidal antiinflammatory | ABBOTT LABORATORIES (US) | 1991-07-16 | — | — | US | disclosed |
| WO-1991008744-A1 | THIAZOLE LIPOXYGENASE-INHIBITING COMPOUNDS DERIVED FROM NON-STEROIDAL ANTIINFLAMMATORY CARBOXYLIC ACIDS | ABBOTT LABORATORIES (US) | 1991-06-27 | — | — | WO | disclosed |
| CN-1030414-A | New thiophene compound and preparation thereof | SANDOZ LTD (CH) | 1989-01-18 | — | — | CN | disclosed |
| EP-0044119-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | STAMICARBON B.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4435552-A | COORDINATION CATALYST CONTAINING HALOACYL COMPOUND | STAMICARBON B.V. (NL) | 1984-03-06 | — | — | US | disclosed |
| EP-0044119-A2 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-20 | — | — | EP | disclosed |