Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738902 | 0.82 | TSHR (0.39) | ALDH1A1TSHRIDO1BCHEAGXT | |
| SCHEMBL7294202 | 0.79 | TSHR (0.43) | ALDH1A1TSHRIDO1AGXTHTR2B | |
| SCHEMBL29552477 | 0.79 | TSHR (0.43) | ALDH1A1TSHRIDO1AGXTHTR2B | |
| SCHEMBL5070648 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1SLC6A2SLC6A3 | |
| SCHEMBL7076809 | 0.79 | TSHR (0.46) | ALDH1A1TSHRIDO1BCHEAGXT | |
| SCHEMBL5555169 | 0.78 | TMEM97 (0.34) | ALDH1A1TSHRHTR2BTMEM97SIGMAR1 | |
| SCHEMBL11734168 | 0.78 | IDO1 (0.34) | ALDH1A1TSHRIDO1AGXTKMT2A | |
| SCHEMBL11633923 | 0.77 | MEN1 (0.51) | TDP1KMT2AMAPTMAPK1 | |
| SCHEMBL11634906 | 0.77 | MEN1 (0.51) | TDP1KMT2AMAPTMAPK1 | |
| SCHEMBL11633919 | 0.77 | MEN1 (0.51) | TDP1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878738-B1 | Anti-inflammatory oxo derivatives and hydroxy derivatives of pyrrolizines, and their pharmaceutical use | MERCKLE GMBH (DE) | 2005-04-12 | — | — | US | disclosed |