Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | CCR8 | P51685 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699910 | 0.98 | CCR1 (0.53) | CCR1CCR5CCR8HRH1METAP2 | |
| SCHEMBL7039186 | 0.95 | CCR1 (0.57) | CCR1CCR5CCR8HRH1METAP2 | |
| Dipyridyl SCHEMBL1923113 | 0.92 | CCR1 (0.46) | CCR1CCR5CCR8HRH1KARS1 | |
| Dipyridyl SCHEMBL1318097 | 0.92 | CCR1 (0.46) | CCR1CCR5CCR8HRH1KARS1 | |
| Dipyridyl SCHEMBL5004969 | 0.90 | CCR1 (0.45) | CCR1CCR5CCR8HRH1KARS1 | |
| Dipyridyl SCHEMBL701722 | 0.90 | CCR1 (0.45) | CCR1CCR5CCR8HRH1KARS1 | |
| SCHEMBL352289 | 0.88 | CCR1 (0.61) | CCR1CCR5CCR8METAP2KARS1 | |
| Dipyridyl SCHEMBL3126694 | 0.85 | CCR1 (0.40) | CCR1CCR5CCR8HRH1KARS1 | |
| SCHEMBL23037127 | 0.84 | CCR1 (0.71) | CCR1CCR5CCR8METAP2KARS1 | |
| SCHEMBL29693673 | 0.84 | CCR1 (0.71) | CCR1CCR5CCR8METAP2KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916606-B2 | Electrochemiluminescent assays | BIOVERIS CORPORATION (US) | 2005-07-12 | — | — | US | disclosed |
| US-20050106652-A1 | Detecting coliform bacteria in food liquids and/or homogenates; immunoassay | BIOVERIS CORPORATION | 2005-05-19 | — | — | US | disclosed |
| US-6703210-B2 | MONITORING CONCENTRATION OF PREFERENTIAL PARTICLES IN SAMPLE; LINK HAPTEN AND ANTIGEN, INCUBATE WITH ANTIBODY JOINED TO ELECTRODE, OXIDIZE OR REDUCE COMPLEX, MONITOR EMITTED LIGHT AND EVALUATE CONCENTRATION OF PREFERENTIAL PARTICLES | SATAKE CORPORATION (JP) | 2004-03-09 | — | — | US | disclosed |
| WO-2003003008-A1 | CHEMICAL LIBRARIES USEFUL FOR DRUG DISCOVERY PROCESSES | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| WO-2003003009-A1 | USE OF METAL-ION CHELATES IN VALIDATING BIOLOGICAL MOLECULES AS DRUG TARGETS IN TEST ANIMAL MODELS | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |
| US-20020052051-A1 | Method and device for determining concentration of dioxins | SATAKE CORPORATION (JP) | 2002-05-02 | — | — | US | disclosed |
| EP-0658564-B1 | Electroluminescent compounds and intermediates in their synthesis | IGEN INT INC (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6316607-B1 | AS LABLES IN DETECTING AND QUANTIFYING CHEMICAL, BIOCHEMICAL, AND BIOLOGICAL SUBSTANCES, DRUGS, METABOLITES, MICROORGANISMS | IGEN INTERNATIONAL, INC. | 2001-11-13 | — | — | US | disclosed |
| EP-0265519-B1 | ELECTROCHEMILUMINESCENT ASSAYS | IGEN INC (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0658564-A1 | Electroluminescent compounds and intermediates in their synthesis | IGEN, INC. (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0647849-A2 | Detecting the presence of analytes in a sample | IGEN, INC. (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0265519-A4 | ELECTROCHEMILUMINESCENT ASSAYS. | IGEN INC (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0265519-A1 | ELECTROCHEMILUMINESCENT ASSAYS. | IGEN INC (US) | 1988-05-04 | — | — | EP | disclosed |
| WO-1987006706-A1 | ELECTROCHEMILUMINESCENT ASSAYS | IGEN, INC. (US) | 1987-11-05 | — | — | WO | disclosed |