Dipyridyl

Dipyridyl

SCHEMBL5004969

Cc1ccnc(-c2cc(CCCCN)ccn2)c1.[Ru].c1ccc(-c2ccccn2)nc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.45
CCR5 P51681 2/20 0.45
CCR8 P51685 2/20 0.45
HRH1 P35367 5/20 0.43
SIGMAR1 Q99720 1/20 0.40
KARS1 Q15046 2/20 0.40
FAAH O00519 1/20 0.39
CES1 P23141 1/20 0.39
MAOA P21397 1/20 0.39
KCNN1 Q92952 1/20 0.38
KCNN2 Q9H2S1 1/20 0.38
KCNN3 Q9UGI6 1/20 0.38
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SLC2A1 P11166 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL701722 1.00 CCR1 (0.45) CCR1CCR5CCR8HRH1SIGMAR1
Dipyridyl SCHEMBL1318097 0.99 CCR1 (0.46) CCR1CCR5CCR8HRH1SIGMAR1
Dipyridyl SCHEMBL1923113 0.99 CCR1 (0.46) CCR1CCR5CCR8HRH1SIGMAR1
SCHEMBL6699910 0.92 CCR1 (0.53) CCR1CCR5CCR8HRH1KARS1
Dipyridyl SCHEMBL3126694 0.92 CCR1 (0.40) CCR1CCR5CCR8HRH1SIGMAR1
SCHEMBL6494641 0.90 CCR1 (0.55) CCR1CCR5CCR8HRH1KARS1
Dipyridyl SCHEMBL699785 0.87 CCR1 (0.45) CCR1CCR5CCR8SIGMAR1FAAH
Dipyridyl SCHEMBL5007665 0.87 CCR1 (0.45) CCR1CCR5CCR8SIGMAR1FAAH
SCHEMBL7039186 0.86 CCR1 (0.57) CCR1CCR5CCR8HRH1KARS1
Dipyridyl SCHEMBL8658875 0.85 CCR1 (0.46) CCR1CCR5CCR8SIGMAR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0265519-A4 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1990-05-14 EP claimed
EP-0265519-A1 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1988-05-04 EP claimed
WO-1987006706-A1 ELECTROCHEMILUMINESCENT ASSAYS IGEN, INC. (US) 1987-11-05 WO claimed
EP-2954332-A1 NOVEL LIPOCALIN-MUTEIN ASSAYS FOR MEASURING HEPCIDIN CONCENTRATION Pieris AG (DE) 2015-12-16 EP disclosed
WO-2015187519-A1 TSLP ASSAY MERCK SHARP & DOHME CORP. (US) 2015-12-10 WO disclosed
WO-2014122166-A1 NOVEL LIPOCALIN-MUTEIN ASSAYS FOR MEASURING HEPCIDIN CONCENTRATION PIERIS AG (DE) 2014-08-14 WO disclosed
US-7462322-B2 Methods and apparatus for improved luminescence assays BIOVERIS CORPORATION (US) 2008-12-09 US disclosed
EP-1286164-B1 Methods and apparatus for improved luminescence assays BIOVERIS CORP (US) 2007-07-25 EP disclosed
EP-0885393-B1 GRAPHITIC NANOTUBES IN LUMINESCENCE ASSAYS MESO SCALE TECHNOLOGIES LLC (US) 2007-05-30 EP disclosed
EP-0877252-B1 Method and apparatus for luminescence assays BIOVERIS CORP (US) 2007-01-10 EP disclosed
US-20050164410-A1 Methods and apparatus for improved luminescence assays BIOVERIS CORPORATION 2005-07-28 US disclosed
EP-0441894-B1 ELECTROCHEMILUMINESCENT REACTION UTILIZING AMINE-DERIVED REDUCTANT IGEN INC (US) 1997-12-10 EP disclosed
WO-1997033176-A1 GRAPHITIC NANOTUBES IN LUMINESCENCE ASSAYS IGEN, INC. (US) 1997-09-12 WO disclosed
EP-0441875-B1 ENHANCED ELECTROCHEMILUMINESCENCE IGEN INC (US) 1997-07-09 EP disclosed
EP-0757252-A2 Electrochemiluminescent assays IGEN, INC. (US) 1997-02-05 EP disclosed
US-5541113-A Method for detecting an analyte using an electrochemical luminescent transition metal label BECKMAN INSTRUMENTS, INC. (US) 1996-07-30 US disclosed
WO-1992014138-A1 METHOD AND APPARATUS FOR MAGNETIC MICROPARTICULATE BASED LUMINESCENCE ASSAY INCLUDING PLURALITY OF MAGNETS IGEN, INC. (US) 1992-08-20 WO disclosed
EP-0265519-A4 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1990-05-14 EP disclosed
EP-0265519-A1 ELECTROCHEMILUMINESCENT ASSAYS. IGEN INC (US) 1988-05-04 EP disclosed
WO-1987006706-A1 ELECTROCHEMILUMINESCENT ASSAYS IGEN, INC. (US) 1987-11-05 WO disclosed