Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.57 |
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494641 | 0.95 | CCR1 (0.55) | CCR1CCR5CCR8METAP2HRH1 | |
| SCHEMBL6699910 | 0.94 | CCR1 (0.53) | CCR1CCR5CCR8METAP2HRH1 | |
| SCHEMBL352289 | 0.90 | CCR1 (0.61) | CCR1CCR5CCR8METAP2TAAR1 | |
| Dipyridyl SCHEMBL1923113 | 0.87 | CCR1 (0.46) | CCR1CCR5CCR8HRH1TAAR1 | |
| Dipyridyl SCHEMBL1318097 | 0.87 | CCR1 (0.46) | CCR1CCR5CCR8HRH1TAAR1 | |
| Dipyridyl SCHEMBL5004969 | 0.86 | CCR1 (0.45) | CCR1CCR5CCR8HRH1TAAR1 | |
| Dipyridyl SCHEMBL701722 | 0.86 | CCR1 (0.45) | CCR1CCR5CCR8HRH1TAAR1 | |
| SCHEMBL23037127 | 0.86 | CCR1 (0.71) | CCR1CCR5CCR8METAP2KARS1 | |
| SCHEMBL29693673 | 0.86 | CCR1 (0.71) | CCR1CCR5CCR8METAP2KARS1 | |
| SCHEMBL23011740 | 0.85 | CCR1 (0.59) | CCR1CCR5CCR8METAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055477-A1 | METHOD FOR THE TREATMENT OF MC RECEPTOR RELATED DISORDERS WITH A CHELATE AND/OR A CHELATOR | 7TM PHARMA A/S (DK) | 2003-07-10 | — | — | WO | disclosed |
| WO-2003003008-A1 | CHEMICAL LIBRARIES USEFUL FOR DRUG DISCOVERY PROCESSES | 7TM PHARMA A/S (DK) | 2003-01-09 | — | — | WO | disclosed |