Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL6494710 | 0.88 | KMT2A (0.41) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL29704023 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL10339146 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL28687178 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL9620663 | 0.78 | HSD17B10 (0.45) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL17865897 | 0.76 | L3MBTL1 (0.37) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| Calcium SCHEMBL9133367 | 0.76 | HSD17B10 (0.43) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| Magnesium SCHEMBL9128595 | 0.76 | HSD17B10 (0.43) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL9132971 | 0.76 | HSD17B10 (0.43) | ALDH1A1HSD17B10KMT2AMAPTLMNA | |
| SCHEMBL3714585 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010637-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-01-11 | — | — | US | disclosed |
| EP-4196474-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| CN-116113630-A | Process for preparing pyridazinone derivatives | 先正达农作物保护股份公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |
| US-6867218-B2 | Compounds, their preparation and use | NOVO NORDISK A/S (DK) | 2005-03-15 | — | — | US | disclosed |
| EP-0884375-B1 | Reaction products of substituted carboxylic acylating agents and carboxylic reactants for use in fuels and lubricants | LUBRIZOL CORP (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1140346-B1 | EMULSION COMPOSITIONS | LUBRIZOL CORP (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1140732-B1 | EMULSION EXPLOSIVE COMPOSITIONS | LUBRIZOL CORP (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20030195200-A1 | Compounds, their preparation and use | VTVX HOLDINGS II LLC | 2003-10-16 | — | — | US | disclosed |
| US-5777142-A | Unsaturated hydroxycarboxylic compounds useful as intermediates for preparing lubricant and fuel additives | THE LUBRIZOL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0823471-A1 | Acylated nitrogen compounds useful as additives for lubricating oil and fuel compositions and intermediates useful for preparing same | The Lubrizol Corporation (US) | 1998-02-11 | — | — | EP | disclosed |
| US-5696067-A | REACTING CERTAIN CARBOXYLIC REACTANTS WITH OLEFINIC COMPOUNDS THEN REACTING THE PRODUCT WITH AMMONIA, A HYDRAZINE OR AN AMINE | THE LUBRIZOL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| US-5696060-A | REACTING OLEFINIC COMPOUNDS WITH CARBOXYLIC COMPOUNDS WHICH ALSO HAVE ANOTHER OXYGEN-CONTAINING GROUP THEN WITH AMMONIA, HYDRAZINES OR AMINE COMPOUNDS YIELDS ADDITIVE CONCENTRATES | THE LUBRIZOL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| US-5686622-A | Thiazolidine derivatives, their preparation and the medicaments containing the same | RHONE-POULENC RORER S.A. (FR) | 1997-11-11 | — | — | US | disclosed |
| EP-0802255-A2 | Hydroxy-group containing acylated nitrogen compositions useful as additives for lubricating oil and fuel compositions | The Lubrizol Corporation (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0802256-A2 | Acylated nitrogen compounds useful as additives for lubricating oil and fuel compositions | The Lubrizol Corporation (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0759435-A2 | Process for preparing compositions useful as intermediates for preparing lubricating oil and fuel additives | The Lubrizol Corporation (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0759444-A2 | Unsaturated hydroxycarboxylic compounds useful as intermediates for preparing lubricant and fuel additives | The Lubrizol Corporation (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0759443-A2 | Hydroxy-substituted monolactones useful as intermediates for preparing lubricating oil and fuel additives | The Lubrizol Corporation (US) | 1997-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010637-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | DHPS, CYP3A4, CYP4B1 | ALDH1A1 192/4885HSD17B10 503/4885KMT2A 2000/4885 |
| US-20030195200-A1 | Compounds, their preparation and use | PPARG, PPARA, PPARD | ALDH1A1 257/4885HSD17B10 235/4885KMT2A 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.