Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733624 | 0.74 | CALM1 (0.50) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL305339 | 0.72 | CALM1 (0.52) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL8132266 | 0.69 | CALM1 (0.55) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL2339223 | 0.68 | CALM1 (0.42) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL6491993 | 0.67 | CALM1 (0.41) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL11685926 | 0.65 | DHFR (0.52) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL991827 | 0.65 | MAOA (0.50) | MAOAMAOB | |
| SCHEMBL759000 | 0.64 | CALM1 (0.38) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL10714727 | 0.64 | CALM1 (0.42) | SORT1CALM1KMT2AMEN1ELANE | |
| SCHEMBL304780 | 0.64 | TP53 (0.44) | SORT1CALM1ELANECTRCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962263-B1 | Method and installation for removing hazardous coatings | MIEDEN JOHANNES-ALBERT (DE) | 2004-12-01 | — | — | EP | claimed |
| EP-0176963-B1 | PROCESS AND APPARATUS FOR THE SEPARATION OF A COMPLEXLY COMPOSED LOAD FROM LIQUID WASTES SUCH AS INDUSTRIAL WASTE WATERS AND SANITARY LANDFILL LEACHATES | von Beckerath, Kurt, Dr.rer.nat.,Dipl.-Chem. (DE) | 1991-07-24 | — | — | EP | claimed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |