Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 5/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684350 | 0.84 | SCN4A (0.48) | SCN4ANISCHTSHRCYP1A2CYP3A4 | |
| SCHEMBL1592873 | 0.81 | NISCH (0.47) | SCN4ANISCHTSHRCYP1A2CYP3A4 | |
| SCHEMBL31490450 | 0.81 | IRAK4 (0.48) | NISCHTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL104727 | 0.81 | IRAK4 (0.48) | NISCHTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4071169 | 0.79 | ALOX15 (0.44) | SCN4ANISCHTSHRCYP1A2CYP3A4 | |
| SCHEMBL28883167 | 0.79 | IRAK4 (0.47) | NISCHTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31121337 | 0.79 | TSHR (0.43) | SCN4ANISCHTSHRCYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL5891986 | 0.79 | IRAK4 (0.47) | NISCHTSHRCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4624005 | 0.79 | IRAK4 (0.47) | NISCHTSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6693445 | 0.78 | ALOX15 (0.46) | SCN4ANISCHTSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055066-A1 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | LIN, TONG-HO (TW) | 2003-03-20 | — | — | US | claimed |
| WO-2017123860-A1 | SPIROHEPTANE SALICYLAMIDES AND RELATED COMPOUNDS AS INHIBITORS OF ROCK | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-20 | — | — | WO | disclosed |
| US-6846826-B2 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | Chen, Ing-Jun (TW) | 2005-01-25 | — | — | US | disclosed |
| US-20030055066-A1 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | LIN, TONG-HO (TW) | 2003-03-20 | — | — | US | disclosed |
| EP-0040591-B1 | PYRIDOXINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | S.A. SANOFI - LABAZ N.V. (BE) | 1983-06-22 | — | — | EP | disclosed |
| US-4374841-A | HYPOTENSIVE, ADRENERGIC BLOCKING, AND CARDIOTONIC AGENTS; CENTRAL DEPRESSANTS | S. A. LABAZ N.V. (BE) | 1983-02-22 | — | — | US | disclosed |
| US-4119729-A | TREATMENT OF HYPERTENSION | MEAD JOHNSON & COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4067904-A | ANTIARRHYTHMIA, HYPOTENSIVE | MEAD JOHNSON & COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055066-A1 | Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain | KCNH2, ADRB3, KCNH3 | SCN4A 274/4885NISCH 1143/4885TSHR 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.