Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.40 |
| ▸ | PPARA | Q07869 | 13/20 | 0.40 |
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496923 | 0.90 | PPARA (0.45) | PPARDPPARAPPARG | |
| SCHEMBL6497644 | 0.82 | ALDH1A1 (0.43) | PPARDPPARAPPARGMAPTKCNA5 | |
| SCHEMBL6503438 | 0.82 | PPARG (0.44) | PPARDPPARAPPARGMAPT | |
| SCHEMBL5552678 | 0.81 | TRPV1 (0.38) | PPARDPPARAPPARGMAPTKCNA5 | |
| SCHEMBL6495642 | 0.81 | PPARA (0.50) | PPARDPPARAPPARG | |
| SCHEMBL6507710 | 0.80 | PPARG (0.45) | PPARDPPARAPPARG | |
| SCHEMBL5549041 | 0.79 | ALDH1A1 (0.36) | PPARDPPARAPPARGLMNAMAPT | |
| SCHEMBL5549723 | 0.78 | HDAC1 (0.39) | PPARGMAPTKCNA5 | |
| SCHEMBL4335162 | 0.77 | TRPV1 (0.39) | PPARDPPARAPPARGLMNAMAPT | |
| SCHEMBL6498144 | 0.77 | NPY1R (0.37) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222227-A1 | Oxazole-amine compounds for the treatment of neurodegenerative disorders | PFIZER INC | 2005-10-06 | — | — | US | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222227-A1 | Oxazole-amine compounds for the treatment of neurodegenerative disorders | PSEN1, APP, BACE1 | PPARD 4082/4885PPARA 3834/4885PPARG 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.