Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.50 |
| ▸ | PPARD | Q03181 | 16/20 | 0.50 |
| ▸ | PPARG | P37231 | 13/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496923 | 0.89 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL27499408 | 0.87 | HDAC1 (0.42) | PPARAPPARG | |
| SCHEMBL5554890 | 0.84 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL4335123 | 0.84 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4337099 | 0.81 | GLS (0.46) | — | |
| SCHEMBL6654921 | 0.81 | GLS (0.46) | — | |
| SCHEMBL6503438 | 0.81 | PPARG (0.44) | PPARAPPARDPPARG | |
| SCHEMBL6497644 | 0.81 | ALDH1A1 (0.43) | PPARAPPARDPPARG | |
| SCHEMBL5549686 | 0.81 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL6495176 | 0.81 | PPARD (0.40) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |