Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507710 | 0.93 | PPARG (0.45) | PPARGPPARDPPARAOPRK1 | |
| SCHEMBL6497644 | 0.92 | ALDH1A1 (0.43) | PPARGPPARDPPARAMAPTNPSR1 | |
| SCHEMBL6496923 | 0.92 | PPARA (0.45) | PPARGPPARDPPARA | |
| SCHEMBL5549723 | 0.88 | HDAC1 (0.39) | PPARGMAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL6498144 | 0.86 | NPY1R (0.37) | PPARGPPARDPPARARECQL | |
| SCHEMBL6496499 | 0.86 | PPARG (0.39) | PPARGPPARDPPARA | |
| SCHEMBL4337044 | 0.84 | MAPT (0.46) | PPARGKDM4EMAPTNPSR1L3MBTL1 | |
| SCHEMBL4327276 | 0.83 | GLS (0.44) | KDM4EMAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL5549065 | 0.82 | AAK1 (0.34) | PPARGMAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL6495176 | 0.82 | PPARD (0.40) | PPARGPPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |