Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495673 | 0.82 | MEN1 (0.49) | CHRM3CHRM2OPRL1OPRM1OPRK1 | |
| SCHEMBL4585565 | 0.82 | LTA4H (0.60) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL18660281 | 0.82 | MEN1 (0.45) | CHRM3CHRM2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6491848 | 0.81 | LTA4H (0.65) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL11217794 | 0.77 | OPRL1 (0.57) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL23296895 | 0.76 | CHRM2 (0.54) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL6223173 | 0.75 | LTA4H (0.59) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL5093540 | 0.75 | KMT2A (0.73) | CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31437068 | 0.75 | CHRM3 (0.61) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL11390291 | 0.74 | CHRM2 (0.60) | CHRM3CHRM2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949550-B2 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-27 | — | — | US | disclosed |
| US-20030212054-A1 | Substituted amino methyl factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212054-A1 | Substituted amino methyl factor Xa inhibitors | F11, F10, F9 | CHRM3 3875/4885CHRM2 3860/4885DRD2 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.