Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495611 | 0.84 | PPARG (0.49) | POLBMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL6505343 | 0.83 | POLB (0.44) | POLBMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL6497351 | 0.83 | POLB (0.43) | POLBMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL6496485 | 0.82 | HSD17B10 (0.52) | POLBMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL6503265 | 0.82 | HPGD (0.56) | MAPTHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL6494358 | 0.81 | MAPT (0.43) | POLBMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL6502012 | 0.81 | PIN1 (0.48) | POLB | |
| SCHEMBL6505813 | 0.80 | PPARA (0.43) | POLBMAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL6503163 | 0.80 | PPARA (0.41) | POLBMAPTLMNASMN1; SMN2GAA | |
| SCHEMBL6503221 | 0.77 | MAPT (0.54) | MAPTALDH1A1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |