Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.48 |
| ▸ | PHGDH | O43175 | 9/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495611 | 0.85 | PPARG (0.49) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6505813 | 0.85 | PPARA (0.43) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6502018 | 0.83 | PHGDH (0.55) | PIN1PHGDH | |
| SCHEMBL6496022 | 0.82 | PPARA (0.48) | PHGDHPPARAPPARGPPARD | |
| SCHEMBL6503221 | 0.82 | MAPT (0.54) | — | |
| SCHEMBL6505343 | 0.81 | POLB (0.44) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6503163 | 0.81 | PPARA (0.41) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6496490 | 0.81 | POLB (0.65) | POLB | |
| SCHEMBL6497351 | 0.79 | POLB (0.43) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6494358 | 0.79 | MAPT (0.43) | PPARAPPARDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |