Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503163 | 0.85 | PPARA (0.41) | PPARAPPARGPPARDPOLBMAPT | |
| SCHEMBL6502012 | 0.85 | PIN1 (0.48) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6505343 | 0.84 | POLB (0.44) | PPARAPPARGPPARDPOLBMAPT | |
| SCHEMBL6505823 | 0.84 | KMT2A (0.41) | PPARAPPARGPPARD | |
| SCHEMBL6497351 | 0.82 | POLB (0.43) | PPARAPPARGPPARDPOLBMAPT | |
| SCHEMBL6495611 | 0.81 | PPARG (0.49) | PPARAPPARGPPARDPOLBMAPT | |
| SCHEMBL6503221 | 0.81 | MAPT (0.54) | MAPTTP53SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6496490 | 0.80 | POLB (0.65) | POLBMAPTTP53HPGDSMN1; SMN2 | |
| SCHEMBL6494358 | 0.78 | MAPT (0.43) | PPARAPPARDPOLBMAPTTP53 | |
| SCHEMBL6504378 | 0.76 | PPARD (0.40) | PPARAPPARGPPARDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |