SCHEMBL651384

SCHEMBL651384

Nc1ccc(Oc2ccc(-c3ccc(Oc4ccc(N)cc4C(F)(F)F)cc3)cc2)c(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
GAA P10253 2/20 0.48
GLA P06280 1/20 0.48
POLB P06746 1/20 0.48
KIF11 P52732 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.43
RAB9A P51151 1/20 0.43
MAPT P10636 3/20 0.40
LMNA P02545 1/20 0.40
ATM Q13315 1/20 0.40
SCN9A Q15858 8/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NCOA1 Q15788 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MITF O75030 1/20 0.36
GFER P55789 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680721 1.00 TSHR (0.48) TSHRGAAGLAPOLBKIF11
SCHEMBL29352455 0.95 TSHR (0.53) TSHRGAAGLAPOLBKIF11
SCHEMBL649657 0.95 TSHR (0.53) TSHRGAAGLAPOLBKIF11
SCHEMBL1352801 0.93 TSHR (0.52) TSHRGAAGLAPOLBKIF11
SCHEMBL7187793 0.93 TSHR (0.52) TSHRGAAGLAPOLBL3MBTL1
SCHEMBL29448858 0.93 TSHR (0.52) TSHRGAAGLAPOLBKIF11
SCHEMBL13114513 0.92 TEAD4 (0.47) TSHRGAAGLAPOLBKIF11
SCHEMBL12689646 0.91 GLA (0.41) TSHRGAAGLAPOLBKIF11
SCHEMBL26037417 0.91 AR (0.42) TSHRGAAGLAPOLBKIF11
SCHEMBL8923663 0.90 KIF11 (0.50) TSHRGAAGLAPOLBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 626 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630739-B2 Polyimide precursor composition and optical multilayer structure formed using the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US claimed
US-12619010-B2 Optical multilayer structure and method of manufacturing the same SK INNOVATION CO., LTD. (KR) 2026-05-05 US claimed
US-20250353961-A1 METHOD FOR EXTENSION OF THE SHELF LIFE OF POSITIVE TYPE PHOTOSENSITIVE POLYIMIDE PRECURSORS IN SOLUTION AKRON POLYMER SYSTEMS INC (US) 2025-11-20 US claimed
US-12411267-B2 Optical multilayer structure and method for manufacturing the same SK INNOVATION CO., LTD. (KR) 2025-09-09 US claimed
WO-2025128627-A1 FLUORINATED THERMOPLASTIC POLYURETHANE ABIOMED, INC. (US) 2025-06-19 WO claimed
US-20250188216-A1 FLUORINATED THERMOPLASTIC POLYURETHANE ABIOMED, INC. (US) 2025-06-12 US claimed
US-20250109251-A1 OPTICAL FILM AND METHOD OF PREPARING SAME KOLON INDUSTRIES, INC. (KR) 2025-04-03 US claimed
CN-119463793-A Fluorine-containing soluble polyimide adhesive special for lithium battery and preparation method and application thereof 中国地质大学(北京) 2025-02-18 CN claimed
WO-2025030690-A1 SOLUBLE POLYIMIDE CASTING SOLUTION, THERMOPLASTIC POLYIMIDE FILM SINTERING LINE AND PREPARATION METHOD THEREFOR AND USE THEREOF 合肥汉之和新材料科技有限公司 2025-02-13 WO claimed
CN-119081403-A High Wen Mose shape memory polyimide film and preparation method and application thereof 哈尔滨工业大学 2024-12-06 CN claimed
WO-2009045537-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2009-04-09 WO claimed
JP-2009506349-A 2009-02-12 JP claimed
US-7459047-B2 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US claimed
US-7438957-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKON POLYMER SYSTEMS (US) 2008-10-21 US claimed
EP-1904603-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS Akron Polymer Systems (US) 2008-04-02 EP claimed
WO-2007011911-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2007-01-25 WO claimed
US-20070014938-A1 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS, INC. 2007-01-18 US claimed
US-5649045-A ADJUSTABLE REFRACTIVE INDEX, CONTROLLABLE BIREFRINGENCE, LOW OPTICAL LOSSES, LOW OPTICAL ABSORBANCE, SOLVENT RESISTANCE, HIGH THERMAL STABILITY; CORE AND CLADDING, ONE OF WHICH CONTAINS A TETRACARBOXYBIPHENYL DIANHYDRIDE MOIETY AMOCO CORPORATION (US) 1997-07-15 US claimed
EP-0779314-A2 Polyimide optical waveguide structures AMOCO CORPORATION (US) 1997-06-18 EP claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12619010-B2 Optical multilayer structure and method of manufacturing the same UHRF1, ASH2L, UBAP2L TSHR 1571/4885GAA 4382/4885GLA 1544/4885
US-12630739-B2 Polyimide precursor composition and optical multilayer structure formed using the same PUF60, ZW10, UBAP2L TSHR 2919/4885GAA 4415/4885GLA 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.