Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 4/20 | 0.68 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770320 | 0.88 | TSHR (0.68) | AKR1C2AKR1C1XDHSMN1; SMN2TSHR | |
| SCHEMBL3417670 | 0.85 | TSHR (0.70) | AKR1C2AKR1C1FTOXDHSMN1; SMN2 | |
| SCHEMBL120353 | 0.85 | ACMSD (0.63) | AKR1C2AKR1C1MCL1FTOXDH | |
| SCHEMBL6508314 | 0.84 | AKR1C2 (0.70) | AKR1C2AKR1C1MCL1FTOXDH | |
| SCHEMBL336771 | 0.84 | SMN1; SMN2 (0.63) | AKR1C2AKR1C1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL18688873 | 0.83 | XDH (0.60) | AKR1C2AKR1C1XDHSMN1; SMN2TSHR | |
| SCHEMBL30784621 | 0.83 | XDH (0.60) | AKR1C2AKR1C1XDHSMN1; SMN2TSHR | |
| SCHEMBL16351974 | 0.82 | MCL1 (0.72) | AKR1C2AKR1C1MCL1FTOXDH | |
| SCHEMBL2560422 | 0.82 | XDH (0.56) | AKR1C2AKR1C1XDHSMN1; SMN2TSHR | |
| SCHEMBL4527705 | 0.81 | XDH (0.55) | AKR1C2AKR1C1XDHSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |