SCHEMBL336771

SCHEMBL336771

Cc1ccc(C(=O)O)c(Cl)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.63
TSHR P16473 1/20 0.63
CASP1 P29466 1/20 0.63
MYC P01106 1/20 0.58
NR4A1 P22736 1/20 0.58
PPARG P37231 1/20 0.55
PPARA Q07869 1/20 0.55
CSNK2A1 P68400 1/20 0.55
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HPGD P15428 3/20 0.51
AKR1C2 P52895 1/20 0.51
AKR1C1 Q04828 1/20 0.51
CLCN2 P51788 1/20 0.51
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
ALDH1A1 P00352 2/20 0.50
PKM P14618 1/20 0.50
GABRA1 P14867 1/20 0.49
GABRG2 P18507 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23070442 0.84 HPGD (0.53) SMN1; SMN2MEN1KMT2AHPGDNPC1
SCHEMBL6496649 0.84 AKR1C2 (0.68) SMN1; SMN2TSHRCASP1MYCNR4A1
SCHEMBL29826380 0.84 AKR1C3 (0.57) SMN1; SMN2TSHRCASP1NR4A1PPARG
SCHEMBL11235643 0.83 POLB (0.50) SMN1; SMN2TSHRCASP1MYCNR4A1
SCHEMBL845424 0.83 GABRA1 (0.53) SMN1; SMN2PPARGPPARAMEN1KMT2A
SCHEMBL670210 0.83 HPGD (0.51) SMN1; SMN2PPARGPPARAMEN1KMT2A
SCHEMBL306765 0.83 ALDH1A1 (0.63) SMN1; SMN2TSHRCASP1PPARGPPARA
SCHEMBL29082496 0.82 SMN1; SMN2 (0.45) SMN1; SMN2TSHRCASP1MYCNR4A1
SCHEMBL29082800 0.81 RAB9A (0.44) SMN1; SMN2TSHRCASP1MYCNR4A1
SCHEMBL2468939 0.81 NPC1 (0.55) SMN1; SMN2MEN1KMT2AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-113845414-B Method for synthesizing 2, 6-naphthalene dicarboxylic acid 中化学科学技术研究有限公司 2022-03-04 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
EP-3551633-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
EP-3551634-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
CN-109369435-A Tolfenamic Acid haptens, artificial antigen and antibody and its preparation method and application 北京勤邦生物技术有限公司 2019-02-22 CN claimed
CN-109212056-A The gas chromatography-mass spectrometry of three kinds of trace monohaloalkyl methyl benzoic acids in a kind of measurement source water 丁立平 2019-01-15 CN claimed
WO-2018108231-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
WO-2018108230-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
EP-1240130-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2002-09-18 EP claimed
EP-1235781-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2002-09-04 EP claimed
EP-1235782-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2002-09-04 EP claimed
US-6399790-B1 USING METAL CATALYST GENERAL ELECTRIC COMPANY 2002-06-04 US claimed
WO-2001038281-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO claimed
WO-2001038282-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO claimed
WO-2001038280-A1 METHOD FOR OXIDATION OF XYLENE DERIVATIVES GENERAL ELECTRIC COMPANY (US) 2001-05-31 WO claimed
EP-0244167-B1 IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) AMOCO CORPORATION (US) 1990-04-04 EP claimed
US-4748227-A Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst AMOCO CORPORATION (US) 1988-05-31 US claimed
EP-0244167-A1 Improved process for preparing poly (aryl ethers) and poly (aryl ether ketones) AMOCO CORPORATION (US) 1987-11-04 EP claimed