Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884328 | 0.72 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL2177064 | 0.71 | MAPT (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL9323981 | 0.70 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL7117428 | 0.70 | HPGDS (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL14072015 | 0.69 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL7469061 | 0.69 | KDM4E (0.41) | SMN1; SMN2MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL15956900 | 0.69 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL20477417 | 0.69 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| SCHEMBL19180075 | 0.68 | CYP1A2 (0.64) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A | |
| Biphenyl SCHEMBL927814 | 0.68 | MEN1 (0.67) | ALDH1A1SMN1; SMN2LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | ALDH1A1 240/4885SMN1; SMN2 4793/4885LMNA 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.