Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504267 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL6502821 | 0.84 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL5762506 | 0.82 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL5760134 | 0.81 | LMNA (0.46) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL1381669 | 0.81 | LMNA (0.49) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL5762896 | 0.81 | LMNA (0.47) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL5786538 | 0.81 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL5788028 | 0.81 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL1381713 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA | |
| SCHEMBL6494942 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | claimed |
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | ALDH1A1 240/4885SMN1; SMN2 4793/4885KDM4E 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.