Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496923 | 0.83 | PPARA (0.45) | — | |
| SCHEMBL5549041 | 0.82 | ALDH1A1 (0.36) | MAPTNPSR1L3MBTL1RECQLTDP1 | |
| SCHEMBL5549029 | 0.81 | PPARD (0.33) | AAK1MAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL5552685 | 0.81 | PPARD (0.44) | AAK1MAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL6503438 | 0.81 | PPARG (0.44) | MAPTNPSR1L3MBTL1RECQLTDP1 | |
| SCHEMBL5549723 | 0.81 | HDAC1 (0.39) | MAPTNPSR1L3MBTL1RECQLTDP1 | |
| SCHEMBL5552678 | 0.79 | TRPV1 (0.38) | AAK1MAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL4327276 | 0.79 | GLS (0.44) | MAPTNPSR1L3MBTL1RECQLTDP1 | |
| SCHEMBL5549709 | 0.79 | NSD2 (0.34) | AAK1MAPTNPSR1L3MBTL1RECQL | |
| SCHEMBL5553488 | 0.79 | KCNA5 (0.33) | AAK1MAPTNPSR1L3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |