Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505651 | 0.80 | HPGD (0.49) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL6497330 | 0.79 | PTPN1 (0.48) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL13846776 | 0.78 | CA2 (0.69) | LMNAALDH1A1CA2POLBMAPT | |
| SCHEMBL6495951 | 0.77 | HPGD (0.53) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL6504802 | 0.76 | HTT (0.55) | LMNAHPGDCA2HTTPOLB | |
| SCHEMBL6498700 | 0.75 | HPGD (0.47) | LMNAHPGDALDH1A1CA2HTT | |
| SCHEMBL6501926 | 0.75 | KMT2A (0.45) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL6496500 | 0.75 | HPGD (0.53) | LMNAHPGDALDH1A1CA2HTT | |
| SCHEMBL6498811 | 0.75 | HPGD (0.48) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL6503843 | 0.75 | MAPT (0.48) | LMNAHPGDALDH1A1CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |