Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15056059 | 0.91 | L3MBTL1 (0.36) | MAPK1LMNAHTTALDH1A1L3MBTL1 | |
| SCHEMBL3279020 | 0.84 | CYP1A2 (0.41) | ALDH1A1L3MBTL1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10526679 | 0.83 | THRB (0.41) | LMNAALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL25182581 | 0.82 | CSNK2A1 (0.40) | HTTALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL5728945 | 0.78 | L3MBTL1 (0.37) | MAPK1ALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL11824469 | 0.76 | — | — | |
| SCHEMBL2350414 | 0.75 | CA12 (0.35) | MAPK1LMNAHTTALDH1A1MAPT | |
| SCHEMBL8768822 | 0.71 | — | — | |
| SCHEMBL16395512 | 0.70 | PDE1A (0.32) | HTT | |
| SCHEMBL6506569 | 0.70 | RIPK1 (0.38) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |