Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.42 |
| ▸ | PPARG | P37231 | 14/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505336 | 0.90 | PPARA (0.53) | PPARAPPARGMMP1PPARD | |
| SCHEMBL7686808 | 0.88 | PPARA (0.44) | PPARAPPARGLDHAMMP1PPARD | |
| SCHEMBL6497980 | 0.85 | PPARA (0.54) | PPARAPPARGMMP1PPARD | |
| SCHEMBL6504364 | 0.85 | PPARG (0.40) | PPARAPPARGLDHAMMP1PPARD | |
| SCHEMBL6505581 | 0.84 | LDHA (0.45) | PPARAPPARGLDHAMMP1PPARD | |
| SCHEMBL6494660 | 0.84 | LDHA (0.41) | PPARAPPARGLDHAMMP1PPARD | |
| SCHEMBL6507864 | 0.82 | MMP1 (0.45) | PPARAPPARGLDHAMMP1PPARD | |
| SCHEMBL6503394 | 0.82 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6496306 | 0.81 | ADRB2 (0.45) | PPARAPPARGLDHAMMP1PPARD | |
| SCHEMBL6497502 | 0.81 | LDHA (0.50) | PPARAPPARGLDHAMMP1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |