Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490952 | 0.91 | ALOX5AP (0.43) | PDE3BPDE3AP2RY12PLA2G2AALOX5AP | |
| SCHEMBL6502820 | 0.87 | ALOX5AP (0.42) | L3MBTL1ALOX5APHPGDMEN1KMT2A | |
| SCHEMBL6489825 | 0.87 | L3MBTL1 (0.43) | L3MBTL1PLA2G2AHPGDMEN1KMT2A | |
| SCHEMBL6920280 | 0.82 | PDE3B (0.42) | PDE3BPDE3AP2RY12ALOX5APMEN1 | |
| SCHEMBL6501253 | 0.80 | L3MBTL1 (0.42) | L3MBTL1HPGDMEN1KMT2APDK2 | |
| SCHEMBL6498632 | 0.80 | PDE3B (0.48) | PDE3BPDE3AP2RY12PLA2G2AALOX5AP | |
| SCHEMBL6495068 | 0.79 | PPARG (0.52) | PDE3BPDE3AP2RY12PLA2G2AALOX5AP | |
| SCHEMBL6488591 | 0.79 | ALOX5AP (0.44) | PLA2G2AALOX5AP | |
| SCHEMBL6497461 | 0.78 | PPARG (0.49) | PDE3BPDE3AP2RY12PLA2G2AALOX5AP | |
| SCHEMBL6487805 | 0.78 | KDM4E (0.42) | L3MBTL1MEN1KMT2ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PDE3B 411/4885PDE3A 733/4885P2RY12 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.