Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490952 | 0.91 | ALOX5AP (0.43) | PDE3BPDE3AP2RY12MCL1PDE2A | |
| SCHEMBL6922928 | 0.86 | MCL1 (0.41) | MCL1FFAR4MEN1KMT2AMAPT | |
| SCHEMBL6497506 | 0.82 | PDE3B (0.43) | PDE3BPDE3AP2RY12ALOX5APMEN1 | |
| SCHEMBL7196037 | 0.82 | PPARG (0.41) | ALOX5APMEN1KMT2A | |
| SCHEMBL6920283 | 0.80 | FFAR4 (0.41) | PDE3BPDE3AP2RY12MCL1PDE2A | |
| SCHEMBL7196031 | 0.80 | MRGPRX4 (0.42) | MCL1ALOX5APMEN1KMT2AMAPT | |
| SCHEMBL6497809 | 0.78 | MCL1 (0.41) | MCL1FFAR4MEN1KMT2AMAPT | |
| SCHEMBL6502820 | 0.76 | ALOX5AP (0.42) | ALOX5APMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL6488591 | 0.74 | ALOX5AP (0.44) | MCL1ALOX5AP | |
| SCHEMBL6501536 | 0.73 | PPARG (0.52) | PDE3BPDE3AP2RY12MCL1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |