Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552676 | 0.85 | PPARA (0.42) | PPARGPPARAPPARDPARP1 | |
| SCHEMBL5549705 | 0.85 | PPARA (0.38) | PPARGPPARAPPARDPARP1L3MBTL1 | |
| SCHEMBL6502624 | 0.84 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6498320 | 0.84 | PPARA (0.45) | PPARGPPARAPPARDHCRTR1HCRTR2 | |
| SCHEMBL5549055 | 0.84 | PPARA (0.43) | PPARGPPARAPPARDPARP1 | |
| SCHEMBL6504835 | 0.84 | PPARG (0.43) | PPARGPPARAPPARDPARP1 | |
| SCHEMBL6497310 | 0.83 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5553473 | 0.83 | PPARA (0.36) | PPARGPPARAPPARDPARP1L3MBTL1 | |
| SCHEMBL5549020 | 0.82 | PPARG (0.39) | PPARGPPARAPPARDPARP1NPC1 | |
| SCHEMBL6496886 | 0.81 | PPARG (0.41) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |