Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487238 | 0.93 | PPARG (0.35) | PPARGPLA2G2APIK3C2BALDH1A1THRB | |
| SCHEMBL6490563 | 0.88 | PPARG (0.45) | PPARGPLA2G2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL6489425 | 0.86 | PPARG (0.36) | PPARGPLA2G2APIK3C2BKDM4ENPC1 | |
| SCHEMBL6490173 | 0.85 | RARB (0.47) | PPARGDCTPP1PTPN11 | |
| SCHEMBL6489619 | 0.85 | PIK3C2B (0.41) | PPARGPIK3C2BKDM4ENPC1ALDH1A1 | |
| SCHEMBL6497730 | 0.84 | PPARG (0.44) | PPARGPLA2G2AMCL1DCTPP1PTPN11 | |
| SCHEMBL6497678 | 0.84 | PTPN11 (0.46) | PPARGPTPN11 | |
| SCHEMBL6498830 | 0.82 | PIK3C2B (0.41) | PPARGPIK3C2BKDM4EALDH1A1DCTPP1 | |
| SCHEMBL6488200 | 0.81 | PPARG (0.43) | PPARGPLA2G2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL6489388 | 0.81 | GABRA1 (0.36) | PPARGPLA2G2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PPARG 233/4885PLA2G2A 4801/4885PIK3C2B 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.