Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497985 | 0.93 | PPARG (0.36) | PPARGTHRBPLA2G2APIK3C2BDCTPP1 | |
| SCHEMBL6488200 | 0.89 | PPARG (0.43) | PPARGTHRBPLA2G2AALDH1A1LMNA | |
| SCHEMBL6489123 | 0.87 | LMNA (0.42) | PPARGPIK3C2BALDH1A1LMNAGABRA2 | |
| SCHEMBL6489265 | 0.84 | TARBP2 (0.42) | PPARGPIK3C2BALDH1A1LMNAGABRA2 | |
| SCHEMBL6489388 | 0.84 | GABRA1 (0.36) | PPARGTHRBPLA2G2ADCTPP1LMNA | |
| SCHEMBL6489090 | 0.84 | PPARG (0.43) | PPARGTHRBDCTPP1LMNAGABRA1 | |
| SCHEMBL6490173 | 0.82 | RARB (0.47) | PPARGDCTPP1 | |
| SCHEMBL6490563 | 0.81 | PPARG (0.45) | PPARGPLA2G2AALDH1A1PPARA | |
| SCHEMBL6489425 | 0.81 | PPARG (0.36) | PPARGTHRBPLA2G2APIK3C2BDCTPP1 | |
| SCHEMBL6497730 | 0.80 | PPARG (0.44) | PPARGPLA2G2ADCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PPARG 233/4885THRB 2919/4885PLA2G2A 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.