Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889845 | 0.85 | SLC6A4 (0.52) | SLC6A4PTGER1FFAR1FFAR2FFAR4 | |
| SCHEMBL22721638 | 0.83 | IDO1 (0.47) | KDM4ETDP1MAPTGAAMEN1 | |
| SCHEMBL6503039 | 0.81 | ALDH1A1 (0.51) | FFAR1FFAR2FFAR4MAPTMEN1 | |
| SCHEMBL12635847 | 0.79 | MEN1 (0.44) | SLC6A4PTGER1KDM4ETDP1MAPT | |
| SCHEMBL668193 | 0.79 | IDO1 (0.57) | ALDH1A1KMT2APTPN1IDO1 | |
| SCHEMBL6494547 | 0.74 | PPARA (0.74) | PPARDPPARA | |
| SCHEMBL3417024 | 0.74 | PPARA (0.50) | PTGER1FFAR1FFAR2FFAR4PPARD | |
| SCHEMBL492736 | 0.73 | IDO1 (0.68) | ALDH1A1KMT2APTPN1IDO1 | |
| SCHEMBL6497980 | 0.73 | PPARA (0.54) | PPARDPPARA | |
| SCHEMBL6557118 | 0.72 | KDM4E (0.55) | KDM4ETDP1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |