Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17864761 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL856842 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL6498113 | 0.81 | SLC6A4 (0.49) | ALDH1A1MEN1KMT2AFFAR1FFAR2 | |
| SCHEMBL8390016 | 0.77 | PTPN1 (0.48) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL17864851 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL6504762 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL18003425 | 0.76 | MAOB (0.47) | POLBMAPT | |
| SCHEMBL3943365 | 0.75 | PPARD (0.58) | ALDH1A1MEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL6504855 | 0.75 | PPARD (0.65) | PPARDPPARA | |
| SCHEMBL15857953 | 0.75 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |