Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA6 | P23280 | 4/20 | 0.33 |
| ▸ | CA7 | P43166 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505320 | 0.98 | MAOA (0.32) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL6244342 | 0.67 | — | — | |
| SCHEMBL11292131 | 0.67 | CA12 (0.39) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL30548748 | 0.66 | MAOA (0.44) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL20495594 | 0.66 | MAOA (0.44) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL11652330 | 0.66 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL1856547 | 0.64 | CA12 (0.37) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL9487364 | 0.64 | DDB1 (0.48) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL6495679 | 0.63 | CSNK2A1 (0.41) | — | |
| SCHEMBL434305 | 0.63 | ABCB1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |