Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | HNF4A | P41235 | 2/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.53 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.51 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769244 | 0.93 | ADRB1 (0.55) | ADRB3ADRB1MKNK1MKNK2MCL1 | |
| SCHEMBL12121775 | 0.88 | PTPN11 (0.60) | ADRB3ADRB1MCL1HNF4AACMSD | |
| SCHEMBL6496898 | 0.88 | KDM4E (0.53) | ADRB3ADRB1MKNK1MKNK2RXRA | |
| SCHEMBL6505249 | 0.88 | ADRB1 (0.52) | ADRB3ADRB1MKNK1MKNK2MCL1 | |
| SCHEMBL4603368 | 0.87 | PTPN11 (0.59) | ADRB3ADRB1MCL1RXRARXRB | |
| SCHEMBL6501061 | 0.86 | TSHR (0.53) | ADRB3ADRB1MKNK1MKNK2LMNA | |
| SCHEMBL4600417 | 0.84 | PTPN11 (0.60) | ADRB3ADRB1MCL1RXRARXRB | |
| SCHEMBL1316077 | 0.83 | MCL1 (0.71) | MCL1HNF4AACMSDDCLRE1ADCLRE1B | |
| SCHEMBL4815310 | 0.82 | RARB (0.58) | ADRB3ADRB1MCL1LMNANPC1 | |
| SCHEMBL504872 | 0.81 | CHEK1 (0.60) | ADRB3ADRB1MKNK1MKNK2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108762-A | Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof | 四川东材科技集团股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118108762-A | Active ester resin with phosphorus and self-extinguishing characteristic structure, and preparation method and application thereof | 四川东材科技集团股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |