Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.44 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769244 | 0.91 | ADRB1 (0.55) | ADRB1ADRB3RARBRARANEK2 | |
| SCHEMBL15630531 | 0.88 | ADRB1 (0.55) | ADRB1ADRB3RARBRARARARG | |
| SCHEMBL4600863 | 0.88 | PTPN11 (0.56) | RARBRARAHSD17B10TSHRCHRNA7 | |
| SCHEMBL6498950 | 0.88 | ADRB3 (0.60) | ADRB1ADRB3NEK2MKNK1MKNK2 | |
| SCHEMBL15048810 | 0.87 | TSHR (0.51) | HSD17B10TSHRKDM4EMEN1KMT2A | |
| SCHEMBL16616127 | 0.85 | TDP1 (0.57) | ADRB1ADRB3MKNK1MKNK2HSD17B10 | |
| SCHEMBL6496898 | 0.85 | KDM4E (0.53) | ADRB1ADRB3RARBRARANEK2 | |
| SCHEMBL3133634 | 0.83 | ALDH1A1 (0.56) | ADRB1ADRB3NEK2HSD17B10MCL1 | |
| SCHEMBL9518777 | 0.78 | DCLRE1B (0.55) | RARBRARAHSD17B10MCL1RARG | |
| SCHEMBL1188345 | 0.78 | TSHR (0.56) | HSD17B10TSHRKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |