Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568776 | 0.92 | CHRM4 (0.52) | CHRM4LTA4HMAOAKDM4E | |
| SCHEMBL5563921 | 0.81 | CHRNA7 (0.42) | CHRM4 | |
| SCHEMBL5563315 | 0.81 | CHRM4 (0.41) | CHRM4 | |
| SCHEMBL5568456 | 0.80 | HTR2A (0.42) | KDM4E | |
| SCHEMBL5567916 | 0.80 | CHRM4 (0.44) | CHRM4 | |
| SCHEMBL6295115 | 0.76 | CHRM4 (0.40) | CHRM4 | |
| SCHEMBL5569687 | 0.76 | CARM1 (0.50) | — | |
| SCHEMBL5568390 | 0.74 | CARM1 (0.52) | CHRM4 | |
| SCHEMBL6300947 | 0.74 | DRD2 (0.42) | CHRM4KDM4E | |
| SCHEMBL5568935 | 0.74 | CARM1 (0.51) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903103-B2 | Linear cyclic ureas | LES LABORATORIES SERVIER (FR) | 2005-06-07 | — | — | US | disclosed |
| US-20030229100-A1 | New linear cyclic ureas | PEGLION JEAN-LOUIS (FR) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229100-A1 | New linear cyclic ureas | GUCY1B1, UACA, GUCY1A1 | CHRM4 1108/4885LTA4H 2598/4885MAOA 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.