Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502042 | 0.85 | CA1 (0.59) | GAAALDH1A1LMNAPTGS2CA1 | |
| SCHEMBL6502761 | 0.85 | KMT2A (0.54) | GAAALDH1A1PTGS1PTGS2CA1 | |
| SCHEMBL6504612 | 0.84 | GAA (0.57) | GAAALDH1A1CA1CA9MEN1 | |
| SCHEMBL13492090 | 0.84 | ALDH1A1 (0.76) | GAAALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL14527359 | 0.76 | HDAC1 (0.68) | GAAALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL13481186 | 0.72 | POLB (0.68) | GAAALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL1982518 | 0.72 | POLB (0.68) | GAAALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL2992964 | 0.72 | ALDH1A1 (1.00) | GAAALDH1A1LMNAPTGS2CA1 | |
| SCHEMBL7553638 | 0.71 | LMNA (0.50) | GAAALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL8387086 | 0.70 | LMNA (0.76) | GAAALDH1A1LMNAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846933-B1 | Antimycobacterial compounds and method for making the same | THE BOARD OF TRUSTEES OF WELLESLEY COLLEGE (US) | 2005-01-25 | — | — | US | disclosed |
| WO-2002043668-A2 | ANTIMYCOBACTERIAL COMPOUNDS AND METHOD FOR MAKING THE SAME | WELLESLEY COLLEGE (US) | 2002-06-06 | — | — | WO | disclosed |