Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | CA1 | P00915 | 3/20 | 0.73 |
| ▸ | CA9 | Q16790 | 3/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MPO | P05164 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988323 | 0.93 | ALDH1A1 (0.86) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL2986200 | 0.91 | ALDH1A1 (0.83) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL3000231 | 0.91 | ALDH1A1 (0.83) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL3935111 | 0.89 | ALDH1A1 (0.79) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL1415953 | 0.89 | TP53 (1.00) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL3001579 | 0.87 | ALDH1A1 (0.76) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL13492090 | 0.87 | ALDH1A1 (0.76) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL13381492 | 0.87 | ALDH1A1 (0.76) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL16785428 | 0.87 | ALDH1A1 (0.76) | ALDH1A1TP53CA1CA9MAOA | |
| SCHEMBL2995413 | 0.86 | ALDH1A1 (0.75) | ALDH1A1TP53CA1CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119322121-A | High-precision detection method for content of related substances of isoniazid injection | 河北龙海药业有限公司 | 2025-01-17 | — | — | CN | claimed |
| US-4758312-A | Adding colorless electrochemically active compound having positive reduction potential | NALCO CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | claimed |
| CN-119322121-A | High-precision detection method for content of related substances of isoniazid injection | 河北龙海药业有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-119322121-A | High-precision detection method for content of related substances of isoniazid injection | 河北龙海药业有限公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20230159471-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-11584725-B2 | Pyrazinoic acid conjugates and hybrid conjugates | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20200140397-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2020-05-07 | — | — | US | disclosed |
| US-20190201414-A1 | INHIBITOR OF HEME DEGRADATION FOR USE TO IMPROVE ANTIBIOTIC TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2019-07-04 | — | — | US | disclosed |
| US-8450368-B2 | Heme oxygenase inhibitors, screening methods for heme oxygenase inhibitors and methods of use of heme oxygenase inhibitors for antimicrobial therapy | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450368-B2 | Heme oxygenase inhibitors, screening methods for heme oxygenase inhibitors and methods of use of heme oxygenase inhibitors for antimicrobial therapy | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) | 2010-07-22 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |
| US-4758312-A | Adding colorless electrochemically active compound having positive reduction potential | NALCO CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0237738-A2 | Method for in situ corrosion detection using electrochemically active compounds | NALCO CHEMICAL COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| US-4683035-A | Method for in situ corrosion detection using electrochemically active compounds | NALCO CHEMICAL COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | ODC1, OTC, ACACB | ALDH1A1 302/4885TP53 2283/4885CA1 2581/4885 |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | HMOX1, HMOX2, PPOX | ALDH1A1 802/4885TP53 3846/4885CA1 4055/4885 |
| US-11584725-B2 | Pyrazinoic acid conjugates and hybrid conjugates | QPCT, RARA, PNKP | ALDH1A1 240/4885TP53 494/4885CA1 2729/4885 |
| US-20200140397-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | QPCT, RARA, PNKP | ALDH1A1 240/4885TP53 494/4885CA1 2729/4885 |
| US-20190201414-A1 | INHIBITOR OF HEME DEGRADATION FOR USE TO IMPROVE ANTIBIOTIC TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTION | HMOX1, HMOX2, PPOX | ALDH1A1 1493/4885TP53 3509/4885CA1 4579/4885 |
| US-20230159471-A1 | PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES | QPCT, RARA, PNKP | ALDH1A1 240/4885TP53 494/4885CA1 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.