Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497177 | 0.91 | DYRK1A (0.42) | MCL1DCTPP1MAPTKMT2APDE3B | |
| SCHEMBL6497299 | 0.89 | PDE3B (0.40) | MCL1DCTPP1MAPTKMT2APDE3B | |
| SCHEMBL6491512 | 0.84 | MCL1 (0.41) | MCL1DCTPP1MAPTKMT2APDE3B | |
| SCHEMBL6502915 | 0.84 | SMN1; SMN2 (0.44) | MCL1MAPTKMT2APDE3BPDE3A | |
| SCHEMBL6488241 | 0.83 | MCL1 (0.43) | MCL1DCTPP1MAPTKMT2APDE3B | |
| SCHEMBL6502699 | 0.83 | MCL1 (0.46) | MCL1DCTPP1MAPTDYRK1A | |
| SCHEMBL6490634 | 0.82 | MCL1 (0.46) | MCL1PPARG | |
| SCHEMBL6499832 | 0.82 | PLA2G2A (0.42) | MCL1DCTPP1MAPTPDE3BPDE3A | |
| SCHEMBL6488675 | 0.82 | PLA2G2A (0.41) | MCL1DCTPP1MAPTKMT2APDE3B | |
| SCHEMBL6487942 | 0.81 | MCL1 (0.42) | MCL1DCTPP1PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MCL1 806/4885DCTPP1 1534/4885MAPT 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.