Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488659 | 0.84 | PPARA (0.43) | PIK3C2BNPSR1HPGDL3MBTL1LMNA | |
| SCHEMBL6491685 | 0.82 | FABP3 (0.46) | PIK3C2BLMNASMN1; SMN2ALOX5AP | |
| SCHEMBL6491218 | 0.82 | CD38 (0.44) | PIK3C2BNPSR1HPGDL3MBTL1LMNA | |
| SCHEMBL7200058 | 0.79 | FABP3 (0.48) | PIK3C2BLMNASMN1; SMN2PIK3CBALOX5AP | |
| SCHEMBL6495987 | 0.79 | PIK3C2B (0.41) | PIK3C2BNPSR1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6501460 | 0.78 | LMNA (0.41) | PIK3C2BL3MBTL1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL6500552 | 0.77 | MRGPRX4 (0.49) | PIK3C2BLMNASMN1; SMN2ALOX5AP | |
| SCHEMBL6172911 | 0.77 | PPARG (0.48) | PIK3C2BNPSR1HPGDL3MBTL1LMNA | |
| SCHEMBL6171656 | 0.77 | PIK3C2B (0.51) | PIK3C2BNPSR1HPGDL3MBTL1LMNA | |
| SCHEMBL6490602 | 0.77 | PPARG (0.41) | NPSR1HPGDL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PIK3C2B 2433/4885NPSR1 4348/4885HPGD 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.