Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 5/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196400 | 0.90 | PIK3C2B (0.40) | FABP3FABP4FABP5PIK3C2BMRGPRX4 | |
| SCHEMBL6491685 | 0.89 | FABP3 (0.46) | FABP3FABP4FABP5PIK3C2BMRGPRX4 | |
| SCHEMBL6495987 | 0.87 | PIK3C2B (0.41) | FABP3FABP4FABP5PIK3C2BMRGPRX4 | |
| SCHEMBL6501562 | 0.84 | NR4A2 (0.57) | MRGPRX4ALOX5AP | |
| SCHEMBL6498704 | 0.84 | P2RX3 (0.45) | MRGPRX4PTGER1LMNASMN1; SMN2 | |
| SCHEMBL6491233 | 0.82 | MRGPRX4 (0.40) | FABP3FABP4FABP5MRGPRX4PTGER1 | |
| SCHEMBL6489657 | 0.81 | KDM4C (0.42) | MRGPRX4ALOX5AP | |
| SCHEMBL6500552 | 0.81 | MRGPRX4 (0.49) | FABP3FABP4FABP5PIK3C2BMRGPRX4 | |
| SCHEMBL6493027 | 0.80 | MCL1 (0.43) | PIK3C2BMRGPRX4 | |
| SCHEMBL6491218 | 0.80 | CD38 (0.44) | PIK3C2BLMNASMN1; SMN2PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |