Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | NSD2 | O96028 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874455 | 0.82 | ALDH1A1 (0.76) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL15935698 | 0.82 | ALDH1A1 (0.94) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL7892719 | 0.81 | ALDH1A1 (0.80) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL15503835 | 0.81 | ALDH1A1 (0.97) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL4873274 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL12272315 | 0.78 | HRH3 (0.74) | ALDH1A1LMNAKMT2AGAAHRH3 | |
| SCHEMBL14595456 | 0.77 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3844533 | 0.77 | ALDH1A1 (0.69) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL15033016 | 0.76 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL12272451 | 0.75 | HRH3 (1.00) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215582-A1 | Substituted pyrrolopyridines | ASTRAZENECA AB (SE) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215582-A1 | Substituted pyrrolopyridines | ITK, WEE1, PDPK1 | ALDH1A1 1591/4885KDM4E 1691/4885LMNA 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.