Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935698 | 0.84 | ALDH1A1 (0.94) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL15503835 | 0.83 | ALDH1A1 (0.97) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4874455 | 0.82 | ALDH1A1 (0.76) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4873274 | 0.81 | ALDH1A1 (0.71) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3844533 | 0.79 | ALDH1A1 (0.69) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL15033016 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6500831 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6400029 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL19190490 | 0.76 | ALDH1A1 (0.64) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL19190655 | 0.75 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021414-A1 | 1-'2-(4-Hydroxyphenyl)-2-hydroxyethyl!-piperidin-4-ol compounds as nmda receptor antagonists | PFIZER, INC. | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021414-A1 | 1-'2-(4-Hydroxyphenyl)-2-hydroxyethyl!-piperidin-4-ol compounds as nmda receptor antagonists | GRIN1, GRIN3A, GRIN2C | ALDH1A1 893/4885LMNA 4874/4885KDM4E 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.