Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490142 | 0.94 | POLB (0.43) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6499252 | 0.93 | POLB (0.47) | MAPTKDM4ETP53LMNASMN1; SMN2 | |
| SCHEMBL6489328 | 0.92 | GCGR (0.42) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6793046 | 0.90 | NPC1 (0.47) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6502168 | 0.90 | NPC1 (0.51) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6498180 | 0.87 | GCGR (0.50) | MAPTTP53LMNAPOLB | |
| SCHEMBL6502572 | 0.86 | SMN1; SMN2 (0.60) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6492802 | 0.86 | POLB (0.47) | MAPTKDM4ETP53LMNASMN1; SMN2 | |
| SCHEMBL6499843 | 0.85 | SMN1; SMN2 (0.47) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6492232 | 0.84 | CYP3A4 (0.41) | RAB9ANPC1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | RAB9A 4382/4885NPC1 100/4885MAPT 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.