Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTTP | P55157 | 2/20 | 0.44 |
| ▸ | APOB | P04114 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488096 | 0.90 | NPC1 (0.49) | IRAK4NPC1RAB9AMAPT | |
| SCHEMBL6491596 | 0.89 | NPC1 (0.53) | SMOIRAK4NPC1RAB9ATRPV1 | |
| SCHEMBL6497765 | 0.88 | SMO (0.51) | SMOTRPV1MTTPAPOBNR3C1 | |
| SCHEMBL6498489 | 0.87 | SMO (0.51) | SMOTRPV1MAPTMTTPAPOB | |
| SCHEMBL6498051 | 0.86 | SMO (0.49) | SMONPC1RAB9ATRPV1MTTP | |
| SCHEMBL6488763 | 0.86 | MTTP (0.51) | SMOIRAK4NPC1RAB9ATRPV1 | |
| SCHEMBL6488178 | 0.86 | SMO (0.52) | SMOTRPV1MTTPAPOBNR3C1 | |
| SCHEMBL6497909 | 0.86 | SMO (0.52) | SMOTRPV1MTTPAPOBNR3C1 | |
| SCHEMBL6490837 | 0.85 | SMO (0.49) | SMONPC1RAB9ATRPV1MAPT | |
| SCHEMBL6488795 | 0.85 | SMO (0.50) | SMONPC1RAB9ATRPV1MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | SMO 2580/4885IRAK4 2963/4885NPC1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.