Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507039 | 0.91 | CCR8 (0.56) | CCR8 | |
| SCHEMBL6497522 | 0.81 | CCR5 (0.52) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL7158747 | 0.77 | CCR8 (0.53) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6499719 | 0.77 | CCR8 (0.53) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6528757 | 0.75 | KDM4E (0.64) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6497855 | 0.74 | CCR8 (0.56) | CCR8 | |
| SCHEMBL6500890 | 0.74 | CCR8 (0.56) | CCR8 | |
| SCHEMBL5410076 | 0.73 | CCR5 (0.52) | CCR8KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL6507204 | 0.73 | CCR8 (0.57) | CCR8 | |
| SCHEMBL15243730 | 0.72 | MBTD1 (0.62) | CCR8KDM4EALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | CCR8 1/4885KDM4E 4617/4885ALDH1A1 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.